A major figure in the music industry with groups Throbbring Gristle and Psychic TV, Genesis P-Orridge has always questioned deviance and sexuality. The director looks at the relationship with his wife, Lady Jaye with whom he began in the 2000s an unprecedented transgender and body experiment : through plastic surgery, they want to become physically similar and constitute the two parts of a new being, a 'pandrogyne' being beyond gender and standards.